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Replenishment of the B cell compartment after doxorubicin‐induced hematopoietic toxicity is facilitated by STAT1
Author(s) -
Datta Sebak,
Parajuli Nirmala,
Tymoszuk Piotr,
Ottina Eleonora,
Parson Walther,
Sgonc Roswitha,
Villunger Andreas,
Doppler Wolfgang
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0113053
Subject(s) - biology , haematopoiesis , toxicity , stat1 , lymphocyte , cancer research , microbiology and biotechnology , immunology , stem cell , signal transduction , medicine
Lymphoid development before differentiation to pre‐B cells is impaired in STAT1‐deficient mice, and apparent in the recovery phase of doxorubicin‐induced hematopoietic toxicity.