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Decreased frequency of CD73 + CD8 + T cells of HIV‐infected patients correlates with immune activation and T cell exhaustion
Author(s) -
Tóth Ilona,
Le Anh Q.,
Hartjen Philip,
Thomssen Adriana,
Matzat Verena,
Lehmann Clara,
Scheurich Christoph,
Beisel Claudia,
Busch Philipp,
Degen Olaf,
Lohse Ansgar W.,
Eiermann Thomas,
Fätkenheuer Gerd,
MeyerOlson Dirk,
Bockhorn Maximilian,
Hauber Joachim,
Lunzen Jan,
Wiesch Julian Schulze
Publication year - 2013
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0113018
Subject(s) - cd8 , biology , immune system , cytotoxic t cell , immunology , adenosine , t cell , microbiology and biotechnology , cancer research , endocrinology , in vitro , biochemistry
Reduced CD73 on T cells in HIV correlates with disease progression, as well as functional CD8+ T cell defects, and is partially reversible by ART.