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Induction of Bcl‐3 by acute binge alcohol results in Toll‐like receptor 4/LPS tolerance
Author(s) -
Bala Shashi,
Tang Alexander,
Catalano Donna,
Petrasek Jan,
Taha Odette,
Kodys Karen,
Szabo Gyongyi
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0112050
Subject(s) - tlr4 , proinflammatory cytokine , tumor necrosis factor alpha , binge drinking , alcohol , biology , gene knockdown , receptor , transcription factor , immunology , pharmacology , cancer research , inflammation , biochemistry , apoptosis , gene , alcohol consumption
Induction of TLR4/LPS tolerance by acute binge alcohol introduces a new aspect of the complex biological effects of this commonly used substance.