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Staphylococcus aureus directly activates eosinophils via platelet‐activating factor receptor
Author(s) -
Hosoki Koa,
Nakamura Akiko,
Nagao Mizuho,
Hiraguchi Yukiko,
Tanida Hisashi,
Tokuda Reiko,
Wada Hideo,
Nobori Tsutomu,
Suga Shigeru,
Fujisawa Takao
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0112009
Subject(s) - eosinophil , biology , phagocytosis , fibronectin , superoxide , immunology , microbiology and biotechnology , extracellular matrix , biochemistry , asthma , enzyme
Staphylococcus aureus (SA) directly activates eosinophils via PAF receptor to induce degranulation, superoxide, and cytokine production, suggesting that SA colonization has pathological significance in atopic dermatitis.