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Inhibitory effect of semaphorin‐3A, a known axon guidance molecule, in the human thymocyte migration induced by CXCL12
Author(s) -
Garcia Flavia,
Lepelletier Yves,
Smaniotto Salete,
HadjSlimane Réda,
Dardenne Mireille,
Hermine Olivier,
Savino Wilson
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0111031
Subject(s) - thymocyte , semaphorin , biology , microbiology and biotechnology , chemokine , chemotaxis , cd8 , cxcr4 , chemokine receptor , plexin , immunology , receptor , immune system , genetics
SEMA‐3A inhibits chemotaxis triggered by CXCL12 in both immature and mature human thymocytes, constituting as a molecule with regulatory role in T cell development.