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Transcriptional activation of the IL31 gene by NFAT and STAT6
Author(s) -
Park Keunhee,
Park JooHong,
Yang WookJin,
Lee JongJoo,
Song MinJi,
Kim HyoungPyo
Publication year - 2012
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0111020
Subject(s) - nfat , biology , stat6 , jurkat cells , microbiology and biotechnology , transcription factor , signal transduction , interleukin 4 , regulation of gene expression , calcineurin , cytokine , gene , t cell , immunology , biochemistry , medicine , immune system , transplantation
NFAT and STAT6 play critical roles as positive regulators in calcium‐ and IL‐4‐mediated induction of IL‐31 gene in Th2 and mast cells.