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Increased metallothionein gene expression, zinc, and zinc‐dependent resistance to apoptosis in circulating monocytes during HIV viremia
Author(s) -
Raymond Andrea D.,
Gekonge Bethsebah,
Giri Malavika S.,
Hancock Aidan,
Papasavvas Emmanouil,
Chehimi Jihed,
Kossevkov Andrew V.,
Nicols Calen,
Yousef Malik,
Mounzer Karam,
Shull Jane,
Kostman Jay,
Showe Louise,
Montaner Luis J.
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0110051
Subject(s) - viremia , biology , monocyte , apoptosis , metallothionein , immune system , gene expression , immunology , intracellular , peripheral blood mononuclear cell , zinc , gene , in vitro , human immunodeficiency virus (hiv) , microbiology and biotechnology , chemistry , biochemistry , organic chemistry
Differential expression of metallothionein genes and high intracellular zinc promote monocyte survival during HIV infection.