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Anti‐inflammatory properties of the PI3K pathway are mediated by IL‐10/DUSP regulation
Author(s) -
Günzl Philipp,
Bauer Kathrin,
Hainzl Eva,
Matt Ulrich,
Dillinger Barbara,
Mahr Benedikt,
Knapp Sylvia,
Binder Bernd R.,
Schabbauer Gernot
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0110001
Subject(s) - pten , pi3k/akt/mtor pathway , biology , inflammation , signal transduction , microbiology and biotechnology , innate immune system , cytokine , mapk/erk pathway , immune system , immunology , cancer research
Activation of the PI3K/PTEN signaling pathway down‐regulates pro‐inflammatory gene expression via up‐regulation of DUSP1.
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