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The membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA – OMVs, without further stimulating their proinflammatory activity on circulating monocytes
Author(s) -
Tavano Regina,
Franzoso Susanna,
Cecchini Paola,
Cartocci Elena,
Oriente Francesca,
Aricò Beatrice,
Papini Emanuele
Publication year - 2009
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0109030
Subject(s) - bacterial adhesin , cd80 , biology , proinflammatory cytokine , bacterial outer membrane , cd86 , microbiology and biotechnology , immune system , immunology , inflammation , t cell , cd40 , escherichia coli , cytotoxic t cell , in vitro , biochemistry , gene
Anti‐Meningococcus B vaccine candidate stimulates macrophages.
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