Open AccessThe development of precision medicine in clinical practice
Author(s) -
He Mingyan,
Xia Jinglin,
Shehab Mohamed,
Wang Xiangdong
Publication year - 2015
Publication title -
clinical and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2001-1326
DOI - 10.1186/s40169-015-0069-y
Subject(s) - precision medicine , personalization , disease , clinical trial , medicine , personalized medicine , clinical practice , health care , intensive care medicine , data science , computer science , bioinformatics , pathology , family medicine , biology , world wide web , economics , economic growth
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the customization of healthcare, with decisions and practices tailored to an individual patient based on their intrinsic biology in addition to clinical “signs and symptoms”. Construction of a standardized model for the integration of data from various platforms is the central mission of the ‘New Disease Management Model’. The model is helpful for the development of new taxonomy of diseases and subtypes, to personalize therapy based on patient genetic profiles. A rapid progression of precision therapy has been made recently. Clinical trials have shown the therapeutic efficacy of discovered and developed therapeutic agents has improved. However, next‐generation drugs would be designed for disease subtypes with more specificity, efficacy and lower toxicity.