Open AccessUse of filter disks or sinus packs for single and repeated measurement of total IgE and house dust mite specific IgE in nasal secretions
Author(s) -
Berings Margot,
De Ruyck Natalie,
Holtappels Gabriële,
Bachert Claus,
Gevaert Philippe
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s4-p18
Subject(s) - immunoglobulin e , house dust mite , medicine , sinus (botany) , immunology , dilution , allergy , mucous membrane of nose , antibody , biology , botany , genus , physics , thermodynamics
Background There is evidence for local production of IgE in the nasal mucosa of patients with allergic rhinitis (AR). Collection of nasal secretions (NS) by validated methods for measurement of local IgE is of great interest. We aimed to compare two methods for collection of NS sinus packs (SP) and filter disks (FD) and to evaluate the suitability of using a fixed dilution instead of a fixed volume when processing.