Open AccessNew insights into the pathogenesis of non‐allergic rhinitis
Author(s) -
Segboer Christine,
Fokkens Wytske,
Drunen van Kees
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s4-p1
Subject(s) - medicine , immunology , allergy , transcriptome , receptor , pathogenesis , mapk/erk pathway , dust mites , gene , gene expression , signal transduction , biology , allergen , microbiology and biotechnology , biochemistry
Background Effective treatment requires a correct diagnosis, however for different subgroups of chronic rhinitis patients differentiation on a clinical level is complicated. In the case of non-allergic rhinitis (NAR) that represents a wide spectrum of diseases, we are also faced with a missing mechanistic or molecular diagnosis. Here we present an unbiased transcriptomic approach on nasal epithelial cells that assess expression differences between chronic rhinitis subgroups.