Open AccessFood sensitisation profiles in school‐aged children from China and Russia
Author(s) -
Datema Mareen,
Versteeg Serge,
Yung Edmund,
Fedorova Olga,
Potts James,
Kummeling Ischa,
FernándezRivas Montserrat,
Ogorodova Ludmilla,
Burney Peter,
Yazdanbakhsh Maria,
Padukudru Anand Mahesh,
Wong Gary,
Van Ree Ronald
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s3-p42
Subject(s) - sensitization , medicine , china , environmental health , shrimp , food allergy , intoxicative inhalant , allergy , food allergens , geography , immunology , toxicology , biology , ecology , archaeology
Shrimp (7-25%) and crab (4-9%) were the most common food sensitizations in Chinese children, except in Hong Kong, where egg (17%) and milk (15%) sensitization was higher than that to shrimp (13%). In all other sites <7% was sensitized to milk and egg. Children from Tomsk were mostly sensitized to hazelnuts and fruits (~6%) and this was associated with birch pollen and Bet v 1 sensitization. Hazelnut sensitization was <4% in China and fruit sensitization was almost absent in Guangzhou. Sensitization to house dust mite (HDM) was exceptionally high in China (p39%), especially in Hong Kong (73%), compared to Tomsk (13%). IgE titers to HDM were significantly lower in Shaoguan (median 2.0 kUA/L) than in Hong Kong and Guangzhou (median 71.8 and 26.2 kUA/L, respectively). Conclusion Sensitization profiles in Tomsk are dominated by birch pollen cross-reactivity, similar to what is common in Central and Northern Europe. In contrast, sensitization to HDM and sea foods dominated the picture in China. Whether house dust mite sensitization is (partly) at the basis of the high prevalence of seafood sensitization (e.g. via Der p 10/tropomyosin) or whether it is the seafoodrich diet, is currently under investigation.