Open AccessThe use of recombinant fish parvalbumin Gad c 1 in the characterisation of fish allergic patients
Author(s) -
Cabral Duarte Fátima,
Costa Ana Célia,
Pereira Barbosa Manuel Augusto,
Pereira Santos Maria Conceição
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s3-p22
Subject(s) - medicine , allergy , anaphylaxis , fish <actinopterygii> , oral food challenge , immunoglobulin e , allergen , food allergy , gastroenterology , immunology , biology , fishery , antibody
Material and methods We selected 55 pts (34M, 21F; average age:7.4 years). All had fish allergy, characterized by positive clinical history, skin-prick tests and serum specific IgE to several fish and Gad c 1 (UniCap, Thermo-Fisher). Oral food challenge was performed to evaluate fish tolerance acquisition. Statistical analysis was performed using GraphPad Prisma version 5.0 (GraphPad Software Inc, SD). Two groups were compared using a paired t test Wilcoxon. P values<0.05 were considered significant.