Open AccessRelevance of IgE to novel kiwi seed allergens evaluated in kiwi allergic children
Author(s) -
Englund Hillevi,
Hidman Johanna,
BengtssonGref Otti,
Nilsson Caroline,
Brostedt Peter
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s3-o24
Subject(s) - kiwi , allergen , immunoglobulin e , medicine , allergy , food allergy , cross reactivity , immunology , storage protein , biology , antigen , cross reactions , food science , biochemistry , antibody , gene
Background Kiwi fruit is a common food allergen and severe allergic reactions are observed. The current diagnostic accuracy is poor with a reported diagnostic sensitivity of 65% in a large European cohort. Recently, two new kiwi allergens were registered, both being storage proteins and both isolated from kiwi seeds. Storage proteins are often linked to severe clinical reactions in other food allergies. The aim of this study was to evaluate sera from Swedish children with documented kiwi allergy, and investigate their IgE-reactivity to purified seed allergens.