Open AccessRelevance of food allergy in the assessment of NSAID‐involved reactions
Author(s) -
SánchezLópez Jaime,
GarcíaMoral Alba,
Cardona Victoria,
Guilarte Mar,
MuñozCano Rosa,
Pascal Mariona,
Rueda Maria,
Picado César,
Valero Antonio,
Bartra Joan
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s3-o22
Subject(s) - medicine , food allergy , allergy , oral food challenge , sensitization , drug allergy , asthma , adverse effect , clinical significance , dermatology , immunology
Method We prospectively recruited all consecutive patients from June 2012 to May 2014 consulting for an NSAID adverse reaction in which a confirmation diagnosis was reached. The practical approach to the diagnosis of hypersensitivity to NSAIDs was performed according to the protocol from the EAACI Task Force on NSAIDs Hypersensitivity. SPTs were also performed to a standard panel of inhalant and food allergens. Food allergy was assessed by a consistent clinical history and a positive SPT to the foods involved. A subgroup of patients diagnosed as NSAIDenhanced food allergy was challenged with the responsible food in the presence and absence of the NSAID to demonstrate the enhanced effect.