
Severe asthma and allergy ‐ should we look for the allergens
Author(s) -
Lazova Snezhina,
Petrova Guergana,
Miteva Dimitrinka,
Papochieva Vera,
Zafirovski Ljupco,
Perenovska Penka
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s2-p16
Subject(s) - medicine , asthma , exhaled nitric oxide , atopy , allergy , immunology , immunoglobulin e , eosinophil , clinical significance , eosinophil cationic protein , inhalation , concomitant , sputum , antibody , spirometry , pathology , anesthesia , tuberculosis
Material and method For a period of 6 months we evaluated medical history data of 29 children with asthma divided into two groups 14 (6 girls, 8 boys) with severe asthma (SA) on high dose combined inhaled corticosteroids (ICS) and 15 (6 girls, 9 boys) with moderate asthma, matched by age to serve as a control group. For all children we performed pulmonary function tests (PFT), nasal smears for eosinophil counts, drew blood for IgE against inhalation and food allergies antibodies detection and ACQ. IgE were detected with the predesigned kit EurolinePediatric.