Open AccessA study of the mechanisms of Anaphylaxis through passive transfer of IgE‐mediated cutaneous reactivity
Author(s) -
Pahlow Mose Anja,
Gotthard Mørtz Charlotte,
Eller Esben,
Inglev Steffansen Signe,
BindslevJensen Carsten
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s1-o9
Subject(s) - medicine , peanut allergy , anaphylaxis , immunoglobulin e , allergy , immunology , allergic reaction , intradermal injection , allergen , systemic reaction , dermatology , food allergy , antibody
Background A large number of questions regarding the mechanisms of anaphylaxis remain unanswered. One such question is the following: what determines the rate at which the allergic reaction propagates from the point of entry of the allergen in the mouth to full-blown systemic response? We present here a study based on the principle of the original experiments by Prausnitz and Kustner. The aim was to study the importance of different serum profiles of patients with peanut allergy on the dissemination of the allergic reaction.