Open AccessThe Serum Cytokines' Network and Th1/Th2 Profile Balance in patients with Chronic Urticaria
Author(s) -
Hamad Muataz Ali,
Mitskevich Nunu,
Machavariani Ketevan
Publication year - 2015
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-5-s1-o7
Subject(s) - atopy , medicine , immunology , allergy , immunoglobulin e , interleukin 10 , cd8 , immune system , antibody
Background Chronic urticaria is a skin disease with an important immunologic profile. There is a great interest not only due to its special clinical manifestation, but also due to its pathogenic mechanism. New data support the participation of ILs (interleukins) in the pathophysiology of CU (chronic urticaria). The aim of this study is to explore the change and its significance of cytokines, comparative characteristics of immune response Th1/Th2 cytokines profiles balance in patients with CU in relation to atopy.