Open AccessHypersensitivity to betalactam antibiotics: a three years characterization of an Immunoallergy Outpatients' Hospital
Author(s) -
Chambel Marta,
Mota Inês,
Gaspar Ângela,
Piedade Susana,
MoraisAlmeida Mário
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s3-p67
Subject(s) - medicine , amoxicillin , penicillin , culprit , cefuroxime , ampicillin , cefazolin , clavulanic acid , antibiotics , cephalosporin , dermatology , pediatrics , microbiology and biotechnology , myocardial infarction , biology
Methods Retrospective analysis of clinical files and results of skin testing and DPT (drug provocation tests) from January 2011 to December 2013. All patients were studied according to standardized diagnostic procedures of ENDA/EAACI: serum sIgE (specific IgE) (ImmunoCAP, ThermoFisher) to penicillin G/V, amoxicillin and ampicillin; skin prick and IDT (intradermal tests) to PPL/MD (DAP, Diater), penicillin G, amoxicillin and cefuroxime with immediate and delayed reading. Other penicillin derivatives/cephalosporins were tested if they were the culprit drug. DPT with culprit drug was performed if previous investigation was negative. In confirmed cases an alternative BL was tested.