Open AccessHypersensitivity to parenteral antibiotics in patients with cystic fibrosis
Author(s) -
Roehmel Jobst,
Schwarz Carsten,
Mehl Anne,
Stock Philippe,
Staab Doris
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s3-p66
Subject(s) - medicine , antibiotics , cystic fibrosis , pediatrics , anaphylaxis , allergy , immunology , microbiology and biotechnology , biology
Background Hypersensitivity reactions to parenteral administered antibiotics (HRPA) are a substantial problem in managing pulmonary disease in Cystic Fibrosis (CF), especially in advanced CF. This group of patients requires a life long antibiotic treatment with extremely high cumulative doses compared to other patients. In our daily routine we observed a growing number of hypersensitivities. Therefore we conducted this observational study to assess HRPA s impact on the daily clinical work with CF, as well as it’s nature, frequency and predisposing risk factors.