Open AccessClinical pattern of liver injury in drug reaction with eosinophilia and systemic symptoms (DRESS): a retrospective study in Taiwan
Author(s) -
Chen KaiLung,
Lin IChun,
Yang HongChih,
Chu ChiaYu
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s3-p18
Subject(s) - medicine , culprit , eosinophilia , liver injury , retrospective cohort study , gastroenterology , adverse drug reaction , medical record , drug , myocardial infarction , psychiatry
Method To investigate the types of liver injury and factors involved, including the chronology, recovery time, relationship with culprit drugs and the pathology correlations, a retrospective study was conducted by reviewing all medical records of DRESS patients diagnosed between Dec. 2000 and Jan. 2013 in the National Taiwan University Hospital Database. DRESS was defined according to the International Registry of Severe Cutaneous Adverse Reactions (RegiSCAR). The pattern of liver damage is classified according to the International Consensus Meeting criteria.