Open AccessThe “nocebo effect” in drug hypersensitivity diagnosis
Author(s) -
Bommarito Luisa,
Mietta Sabrina,
Cadario Gianni
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s3-o9
Subject(s) - medicine , placebo , itching , drug allergy , provocation test , allergy , dermatology , malaise , nausea , angioedema , surgery , pathology , alternative medicine , immunology
Background Placebo-controlled oral drug provocation tests (DPTs) are an important step in drug hypersensitivity diagnosis. Administration of placebo (an inert sostance not detectable from drug) is recommended to avoid psychological influences on the interpretation of DPT results, however actually little is known about how to deal a reaction to placebo and how to go further with the diagnostic procedures.