Open AccessAllergenarrays: low‐cost food allergy diagnosis using allergen extracts‐based microarrays
Author(s) -
Borges JeanPhilippe,
Gironde Camille,
Trouilh Lidwine,
Berteloite Benjamin,
Apoil Andre Pol,
Rouge Pierre,
Barre Annick,
Trevisiol Emmanuelle
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s2-p37
Subject(s) - medicine , allergen , allergy , food allergy , food allergens , food hypersensitivity , immunology
Background The current tools available for diagnosing food allergy include the clinical history, trial elimination diets, diet diaries, skin prick testing (SPT) and allergen-specific serum IgE testing. Since 15 years, development of allergen-based microarrays using recombinant/natural proteins is increasing, resulting in commercially available microarrays to detect specific IgE against more than 100 allergenic compounds. For the moment, the number of available recombinant allergens and the cost of their development limit the enhancement of allergen microarray technology. The goal of our study is to explore and optimize allergen-microarray from food allergen extracts and trying to create a low-cost IgE detecting platform.