Open AccessBasophils response to Pru p 3 and Ara h 9 in patients sensitised to peach under specific immunotherapy
Author(s) -
Gomez Francisca,
Gomez Enrique,
Doña Inmaculada,
Galindo Luisa,
Campo Paloma,
Posadas Teresa,
Torres Maria Jose,
DiazPerales Araceli,
Blanca Miguel,
Mayorga Lina
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s2-o19
Subject(s) - medicine , sublingual immunotherapy , immunotherapy , allergen immunotherapy , allergy , basophil , immunology , allergen , basophil activation , immunoglobulin e , immune system , antibody
Rationale In Southern Europe Pru p3 is the primary sensitizer of plants fruit and it is responsible of severe reactions. Specific immunotherapy (SIT) brings a new perspective to treat those patients. There is a lack of knowledge regarding cellular responses that include changes in the basophil activation during the IT. We aim to analyse early changes in the basophil response to Pru p 3 and other related allergen (Ara h 9) after the first month of sublingual immunotherapy (SLIT).