Open AccessPD43 ‐ Body fat mass is positively associated with pediatric asthma
Author(s) -
Guibas George V,
Manios Yannis,
Xepapadaki Paraskevi,
Moschonis George,
Douladiris Nikolaos,
Mavrogianni Christina,
Papadopoulos Nikolaos G
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s1-p43
Subject(s) - medicine , asthma , wheeze , waist , overweight , anthropometry , obesity , body mass index , bioelectrical impedance analysis , population , logistic regression , cross sectional study , pediatrics , environmental health , pathology
Background Prevalence of pediatric overweight/obesity and pediatric asthma has been on the rise, with both conditions currently reaching epidemic proportions. Their concurrent rise alludes to potentially common characteristics of their pathophysiologic mechanisms; furthermore, excess fat mass may facilitate asthma induction via obesity-related inflammatory mediators, oxidant stress and mechanical chest restriction. However, although such a link is welldocumented in adults, it is not yet established in children. We thus opted to investigate into a potential adiposity/ asthma association in a cross-sectional, population-based study in preschoolers, by using several indices to assess fat mass.