Open AccessPD27 ‐ Specific antibodies in oral immunotherapy for cow's milk allergy: kinetics and prediction of clinical outcome
Author(s) -
Savilahti Emma M,
Kuitunen Mikael,
Mäkelä Mika,
Savilahti Erkki
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s1-p27
Subject(s) - medicine , desensitization (medicine) , immunoglobulin e , ovalbumin , immunology , antibody , allergy , milk allergy , egg white , egg allergy , immunotherapy , immunoglobulin g , gastroenterology , antigen , immune system , biology , receptor , food science
Methods We investigated 40 children aged 6-17 year with cow’s milk allergy who either successfully completed OIT (n=32) or discontinued the therapy due to side effects (n=8). We analyzed in sera drawn before and after OIT specific IgA, IgG, IgG1 and IgG4 to CM, casein, betalactoglobulin and ovalbumin with enzyme linked immunosorbent assay, and IgE to CM and hen’s egg white with enzymatic fluoroimmunoassay (Pharmacia CAP system).