Open AccessP56 ‐ Control of allergic inflammation and erythrocytes magnesium level in children with bronchial asthma
Author(s) -
Shishimorov Ivan,
Perminov Alex,
Gorbunov Vitaly
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s1-p111
Subject(s) - medicine , exhaled nitric oxide , asthma , inflammation , allergic inflammation , allergy , immunology , gastroenterology , magnesium , disease , systemic inflammation , materials science , metallurgy
Results Patients comparison groups had comparable levels of clinical control of asthma by AST-test. In determining the level of nitric oxide in exhaled air were obtained pre-credibility of the differences between the groups. A more pronounced level of allergic inflammation in patients 2 groups confirmed higher concentrations of its laboratory markers. In determining the level of magnesium in red blood cells have lower it with the content of the group 2 patients. Conclusions The study revealed the discrepancy between clinical asthma control level and laboratory markers of allergic inflammation. In patients with longer experience of the disease on a background of basic therapy revealed higher levels of allergic inflammation and lower levels of magnesium in erythrocytes. Pharmacological correction of magnesium levels may be useful to improve the efficiency of basic therapy of asthma and achieve control of allergic inflammation.