Open AccessO22 ‐ Asian Americans demonstrate optimal compliance in CDC recommended pediatric vaccine schedule: implication of immunisation in autism causal inference
Author(s) -
Holmes Larry,
Oceanic Patricia,
Fitzgerald Diane,
Grant Kelli,
Lahurd Alexandra,
Dabney Kirk
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s1-o22
Subject(s) - medicine , vaccination , pacific islanders , tetanus , diphtheria , measles , measles mumps rubella vaccine , hepatitis b , vaccination schedule , immunization , rubella , carriage , pediatrics , demography , immunology , environmental health , population , sociology , pathology , antigen
Results Recipients were Whites/Caucasians, 1,917 (32.7%), Blacks/ African Americans (AA), 2904 (49.5%), Asian, 134 (2.3%), Hawaiian native /Pacific Islander,4 (0.1%), American Indian/Alaskan Native (AI/AN),9(0.2%), and some other race, 727(12.4%). There was overall 92.3% compliance to the recommended schedule. A significant racial variability in MMR as well as HBV were observed, Asian (98.5%), AA (98.4%) and Caucasian (97.1%), c 2 (7)=20.6, p=0.01, and Asians (99.3%), AA(94%) and Caucasian (98.7%), c 2 (7)=23.9, p=0.001 respectively. Asians demonstrated highest compliance in the receipt of varicella (Asians [99.3%], AA [98.6%], and Caucasian [97.1%], c 2 (7)=18.7, p=0.01, and toxoid poliovirus (Asians [100%], AA [99.4%] and Caucasian [99%], c 2 (7)=12.3, p=0.09. Asians (97.0%) relative to AA (93.1%) and Caucasian (91%) demonstrated the highest compliance in all vaccines combined, c 2 (7) =24.5, p=0.001. Caucasians and AA, relative to Asians were 69% (Odds ratio [OR]=0.42, 95% CI, 0.15-1.14, and 58%, (OR=0.31, 95%CI, 0.11-0.85) less likely to adhere to the CDC schedule respectively. However, multivariable model indicated insignificant racial disparities between Asians and Caucasians, adjusted OR, 0.45, 99%CI, 0.08-1.11.