Open AccessO14 ‐ Der p 10 as a minor allergen in children sensitised to house dust mites
Author(s) -
Lafuente Isabel,
Pina Raquel,
Uixera Sonia,
Calderon Rafael,
Cortell Isidoro,
Lopez Juan,
Nieto Antonio,
Mazon Angel
Publication year - 2014
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-4-s1-o14
Subject(s) - medicine , immunoglobulin e , sensitization , dust mites , house dust mite , allergy , asthma , immunology , allergen , antibody
Results We studied 232 children (147 M/85 F) aged 1.25 16.7 years. Negative results were found in 50 (21.6%) with Der p 1, 53 (22.8%) with Der p 2, 208 (89.7%) with Der p 10, and 29 with all three (12.5%). There were 24 patients with positive IgE to Der p 10: three of these had IgE values of 6.1 to 11 kUA/L to Der p 10 and negative results to Der p 1 and 2 (0.1 to 0.18), three had much higher IgE to Der p 10 (79.9 to >100) than to Der p 1 or 2 (0,58 to 24.2), and one slightly higher IgE to Der p 10 (2.8) than to Der p 1 or 2 (0.8 and 1.19). The rest of the patients had clearly lower IgE to Der p 10.