Open AccessSerum imbalance between the extracellular matrix metalloproteinases (MMP‐2 and MMP‐9) and their tissue inhibitor (TIMP‐1) in patients with food and airborne allergy
Author(s) -
Kuźmiński A,
Przybyszewski M,
Graczyk M,
ŻbikowskaGotz M,
Bartuzi Z
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p50
Subject(s) - matrix metalloproteinase , medicine , allergy , extracellular matrix , food allergy , matrix (chemical analysis) , tissue inhibitor of metalloproteinase , immunology , microbiology and biotechnology , biology , materials science , composite material
Methods The study was performed in 80 individuals: 60 patients with exacerbation of allergic disease (30 with food allergy and 30 with airborne allergies) and 20 healthy subjects. We examined the serum concentrations of soluble forms of MMP-2, MMP-9 and TIMP-1. Determination of these parameters was performed by ELISA. For MMP-9 and TIMP-1 was used kit from Bender MedSystems, for MMP-2 of RayBiotech. A statistical study results was performed using the computer program STATISTICA 9.1.