Open AccessNon‐IgE‐mediated food allergy: a tolerance induction protocol
Author(s) -
Arêde C,
Cabral A,
Piedade S,
MoraisAlmeida M
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p19
Subject(s) - medicine , allergy , immunoglobulin e , protocol (science) , immunology , food allergy , antibody , pathology , alternative medicine
Background Cow’s milk proteins allergy (CMPA) is the most common food allergy in childhood, affecting up to 2.5% of infants. The immune mechanisms underlying non-IgE-mediated clinical presentations, which mostly affect the gastrointestinal system and are sometimes very severe, are not fully understood. Currently, specific oral tolerance induction (SOTI) is available as a specific treatment for CMPA, but most studies of this approach have focused on IgEmediated forms of this food allergy.