Open AccessInduction of oral tolerance for cow’s milk proteins. Is everything under control?
Author(s) -
Muñoz Archidona C,
Quevedo Teruel SJ,
Viada Bris JF,
Bracamonte Bermejo T,
Echeverría Zudaire LA
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p17
Subject(s) - medicine , cow's milk allergy , milk allergy , food science , immunology , allergy , food allergy , biology
Methods We evaluated 59 patients with IgE-mediated allergy for CMP on whom we administered IOT treatment according to our protocol. Initial induction phase was made at hospital (up to 2.5ml), followed by a maintenance phase at home, with an increase of the weekly dosage that was performed in the outpatient clinic. Once a dose of 200ml/day was achieved, continued daily dose was taken at home. We did a clinical follow-up at 6 months and then annually, with skin prick tests and specific IgE levels. We pay special attention to the problems and complications that arose during the IOT and its subsequent follow-up.