Open AccessFood allergen thresholds: CM‐allergic infants managed with hypoallergenic formulas are a more sensitive population
Author(s) -
Cordle C,
Williams LW,
DuskaMcEwen G,
Farrow MJ
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p149
Subject(s) - hypoallergenic , medicine , food allergy , allergen , food allergens , allergy , population , immunology , allergic reaction , food hypersensitivity , environmental health
Background Understanding the relationship of food allergen dose to clinical symptoms is important for managing food-allergic patients, the food industry, and regulatory bodies as all strive to insure food safety. Food allergen reactivity thresholds are highly variable depending on the food and the food-allergic patient population. Existing studies describe reaction thresholds for major food allergens that are useful in managing individual patients. Reaction thresholds are not distributed in a statistically “normal” fashion; some infants with cow milk allergy show sensitivity to extremely low doses. Data describing these unique patients is presented.