Open AccessSecondary prevention of peanut allergy – continuous feeding or restriction of peanut protein
Author(s) -
Bellach J,
Niggemann B,
Beyer K,
Ahrens B
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p139
Subject(s) - peanut allergy , medicine , allergy , pediatrics , food allergy , immunoglobulin e , immunology , antibody
Methods In an open study design 460 children aged 5 to 30 months with AE and no detectable peanut-specific serum IgE will be divided into two groups. In Group A parents are advised to feed their children peanut at least three times a week, in Group B participating children strictly avoid peanut in their diet. Children are followed for one year. At the beginning and the end of the study standardized questionnaires are performed, blood samples are collected and medical examination (including SCORAD) is assessed. Children who will develop sensitization to peanut will undergo a double blind placebo controlled food challenge.