Open AccessPeanut allergy in France: preliminary results of the MIRABEL pilot study
Author(s) -
NguyenGrosjean VM
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p131
Subject(s) - medicine , atopy , angioedema , allergy , asthma , atopic dermatitis , sensitization , dermatology , anaphylaxis , ingestion , inhalation , food allergy , immunology , anesthesia
Results Out of 61 patients, 66% were male, aged from 1 to 11 at the time of their first allergic reaction (median: 3 years). Peanut allergy was documented in 52 patients. Sensitization was observed in 9 cases. 95% of patients had atopy: atopic dermatitis (62.3%), asthma (55.7%), allergic rhinitis (47.5%). Associated food sensitizations or allergies were: tree nuts (47.7%), legumes (36.4%), egg (25%),other foods (34.1%). Symptoms were urticaria and/or angioedema (54.1%), digestive symptoms (19.7%), laryngeal angioedema (9.8%), asthma (6.5%), conjunctivitis (5.8%), atopic dermatitis (3.8%) serious systemic reaction (8.3), anaphylactic shock (1.6%). Exposition routes were ingestion (84.6%), skin contact (28.8%), inhalation (5.8%). Foods involved were roasted peanuts (59.6%), Curly (34.6%), aperitive biscuits (17.3%) and others. The reactive amount was quantified in 56% of cases and was infinitesimal in 14.7% of cases. The median of the reactive amount was 102 mg (range:34-1062) of protein equivalent. A strict avoidance needing to read the labels was prescribed in 32.2% of cases, based on a low reactive threshold: median 24 mg (range:4.7-109 mg). Authorized traces were correlated to a higher reactive threshold: median 638 (range: 88-2217) (p=0.005). 50% of questionnaires for consumptions were sent back.