Open AccessConcentration of interleukin 17A and measurement properties of the neutrophiles with food allergy hypersensitivity patients
Author(s) -
ŻbikowskaGotz M,
Pałgan K,
GawrońskaUkleja E,
Kuźmiński A,
Przybyszewski M,
Bartuzi Z
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s3-p104
Subject(s) - immunology , chemokine , elastase , medicine , allergy , neutrophil elastase , secretion , cytokine , chemotaxis , interleukin 8 , neutrophile , inflammation , chemistry , enzyme , biochemistry , receptor
Background IL17 is a cytokine produced by activated helper lymphocytes Th17. It plays a role in the mechanisms of allergic reactions involving neutrophils through the induction of poduction cytokines and chemokines. Affects the activation, recruitment and migration of neutrophils into the tissue by regulating inflammatory reaction. Activated neutrophils secrete elastase and ROS (reactive oxygen derivatives) important mediators of the inflammatory process responsible for tissue damage.