Open AccessPulsating aerosols for the rhinosinusitis treatment – evaluation of an innovative method in a multicentric survey
Author(s) -
Mentzel Heribet W,
Ledermueller Rosina,
Watt Kirsteen
Publication year - 2013
Publication title -
clinical and translational allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.979
H-Index - 37
ISSN - 2045-7022
DOI - 10.1186/2045-7022-3-s2-p38
Subject(s) - medicine , inhalation , paranasal sinuses , sinusitis , chronic rhinosinusitis , quality of life (healthcare) , population , sinus (botany) , pediatrics , surgery , anesthesia , environmental health , botany , biology , genus , nursing
Background Acute and Chronic Rhinosinusitis (ARS/CRS) have a strong healtheconomic impact. It can be assumed that 10-15% of the US and EU population suffers from CRS. The success of topical drug delivery to the sinuses principally desirable is limited because the paranasal cavities are virtually non-ventilated areas. An innovative inhalation system (PARI SINUS) which provides a pulsating aerosol has been shown to improve the particle deposition within the paranasal sinuses compared to an inhalation without vibration. Patients’ acceptance of this device and the clinical effects of the therapy have been evaluated.