Open AccessPossible mechanism and clinical potentials of allostery
Author(s) -
Huang Peixin,
López Villar Elena
Publication year - 2014
Publication title -
clinical and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2001-1326
DOI - 10.1186/2001-1326-3-18
Subject(s) - mechanism (biology) , allosteric regulation , neuroscience , computer science , data science , medicine , psychology , epistemology , philosophy , receptor
Allostery is involved in the dynamic regulation of biological functions in proteins. Advances in allostery research have recently drawn great interest and brought allostery closer to the clinic. The present commentary describes the mechanism by which allostery may involve in from a cell‐wide view and its contribution to the discovery of new therapeutics to diseases.