Open AccessBioinformatics insights into acute lung injury/acute respiratory distress syndrome
Author(s) -
Fang Xiaocong,
Bai Chunxue,
Wang Xiangdong
Publication year - 2012
Publication title -
clinical and translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 1
ISSN - 2001-1326
DOI - 10.1186/2001-1326-1-9
Subject(s) - ards , medicine , disease , bioinformatics , biomarker , pathogenesis , acute respiratory distress , omics , intensive care medicine , computational biology , lung , pathology , biology , biochemistry
Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment.