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T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals
Author(s) -
Nora Philipp,
Maryam Kazerani,
Alyssa Nicholls,
Binje Vick,
Jan Wulf,
Tobias Straub,
Michaela Scheurer,
Amelie Muth,
Gerulf Hänel,
Daniel Nixdorf,
Monika Sponheimer,
Malte Ohlmeyer,
Sonja M. Lacher,
Bettina Brauchle,
Anetta Marcinek,
Lisa Rohrbacher,
Alexandra Leutbecher,
Kai Rejeski,
Oliver Weigert,
Michael von BergweltBaildon,
Sebastian Theurich,
Roman Kischel,
Irmela Jeremias,
Veit Bücklein,
Marion Subklewe
Publication year - 2022
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood.2022015956
Subject(s) - t cell , blinatumomab , medicine , immunotherapy , in vivo , cytokine release syndrome , immunology , immune system , cancer research , chemistry , chimeric antigen receptor , cd19 , biology , microbiology and biotechnology

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