Open AccessEpigenetic therapies in acute myeloid leukemia: where to from here?
Author(s) -
Katie Fennell,
Charles C. Bell,
Mark A. Dawson
Publication year - 2019
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood.2019003262
Subject(s) - myeloid leukemia , epigenetics , medicine , myeloid , leukemia , immune system , immunology , acute leukemia , bioinformatics , biology , genetics , gene
In a Perspective, Fennell et al review the current state of epigenetic therapies for acute myeloid leukemia, highlighting their proposed mechanisms of action, the role of the immune system in mediating their response, and the outlook for new agents and combined therapies to maximize their potential efficacy.
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