Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs | Zendy

Sorcha O’Byrne | Zendy; Natalina Elliott | Zendy; Siobhan Rice | Zendy; Gemma Buck | Zendy; Nicholas Fordham | Zendy; Catherine Garnett | Zendy; Laura Godfrey | Zendy; Nicholas T. Crump | Zendy; Gary Wright | Zendy; Sarah Inglott | Zendy; Hua Peng | Zendy; Bethan Psaila | Zendy; Benjamin Povinelli | Zendy; David J. H. F. Knapp | Zendy; Antonio Agraz-Doblás | Zendy; Clara Bueno | Zendy; Ignacio Varela | Zendy; Phillip R. Bennett | Zendy; Hashem Koohy | Zendy; Suzanne M. Watt | Zendy; Anastasios Karadimitris | Zendy; Adam J. Mead | Zendy; Phillip Ancliff | Zendy; Paresh Vyas | Zendy; Pablo Menéndez | Zendy; Thomas A. Milne | Zendy; Irene Roberts | Zendy; Anindita Roy | Zendy

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Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Author(s) -

Sorcha O’Byrne,

Natalina Elliott,

Siobhan Rice,

Gemma Buck,

Nicholas Fordham,

Catherine Garnett,

Laura Godfrey,

Nicholas T. Crump,

Gary Wright,

Sarah Inglott,

Hua Peng,

Bethan Psaila,

Benjamin Povinelli,

David J. H. F. Knapp,

Antonio Agraz-Doblás,

Clara Bueno,

Ignacio Varela,

Phillip R. Bennett,

Hashem Koohy,

Suzanne M. Watt,

Anastasios Karadimitris,

Adam J. Mead,

Phillip Ancliff,

Paresh Vyas,

Pablo Menéndez,

Thomas A. Milne,

Irene Roberts,

Anindita Roy

Publication year - 2019

Publication title -

blood

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.515

H-Index - 465

eISSN - 1528-0020

pISSN - 0006-4971

DOI - 10.1182/blood.2019001289

Subject(s) - lymphopoiesis , ontogeny , biology , lineage (genetic) , in utero , progenitor cell , progenitor , fetus , b cell , stem cell , immunology , genetics , antibody , pregnancy , gene

By comparing fetal and adult B-lymphopoiesis, the authors identify a prepro–B-cell subset in humans that marks the origin of B-cell lineage commitment in utero.

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