circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression | Zendy

Yu-Meng Sun | Zendy; Wentao Wang | Zendy; ZhanCheng Zeng | Zendy; Tian-Qi Chen | Zendy; Cai Han | Zendy; Qi Pan | Zendy; Wei Huang | Zendy; Ke Fang | Zendy; Lin-Yu Sun | Zendy; Yan-Fei Zhou | Zendy; XueQun Luo | Zendy; Chengwei Luo | Zendy; Xin Du | Zendy; Yujie Chen | Zendy

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circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression

Author(s) -

Yu-Meng Sun,

Wentao Wang,

ZhanCheng Zeng,

Tian-Qi Chen,

Cai Han,

Qi Pan,

Wei Huang,

Ke Fang,

Lin-Yu Sun,

Yan-Fei Zhou,

XueQun Luo,

Chengwei Luo,

Xin Du,

Yujie Chen

Publication year - 2019

Publication title -

blood

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.515

H-Index - 465

eISSN - 1528-0020

pISSN - 0006-4971

DOI - 10.1182/blood.2019000802

Subject(s) - myeloid leukemia , translation (biology) , cancer research , circular rna , npm1 , leukemia , myeloid , medicine , microrna , biology , immunology , genetics , gene , messenger rna , karyotype , chromosome

Sun et al identify a circular RNA, circMYBL2, that upregulates FLT3 translation to promote FLT3-ITD acute myeloid leukemia (AML) progression, suggesting a novel therapeutic target for FLT3-ITD AML.

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