Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome | Zendy

Austin L. Brown | Zendy; Adam J. de Smith | Zendy; Vincent U. Gant | Zendy; Wenjian Yang | Zendy; Michael E. Scheurer | Zendy; Kyle M. Walsh | Zendy; Jonathan M. Chernus | Zendy; Noah A. Kallsen | Zendy; Stephen Peyton | Zendy; Gareth E. Davies | Zendy; Erik A. Ehli | Zendy; Naomi J. Winick | Zendy; Nyla A. Heerema | Zendy; Andrew J. Carroll | Zendy; Michael J. Borowitz | Zendy; Brent L. Wood | Zendy; William L. Carroll | Zendy; Elizabeth A. Raetz | Zendy; Eleanor Feingold | Zendy; Meenakshi Devidas | Zendy; Lisa F. Barcellos | Zendy; Helen M. Hansen | Zendy; Libby M. Morimoto | Zendy; Alice Y. Kang | Zendy; I. Smirnov | Zendy; Jasmine Healy | Zendy; Caroline Laverdière | Zendy; Daniel Sinnett | Zendy; Jeffrey W. Taub | Zendy; Jillian M. Birch | Zendy; Pamela Thompson | Zendy; Logan G. Spector | Zendy; Maria S. PombodeOliveira | Zendy; Andrew T. DeWan | Zendy; Charles G. Mullighan | Zendy; Stephen P. Hunger | Zendy; ChingHon Pui | Zendy; Mig L. Loh | Zendy; Michael E. Zwick | Zendy; Catherine Metayer | Zendy; Xiaomei Ma | Zendy; Beth A. Mueller | Zendy; Stephanie L. Sherman | Zendy; Joseph L. Wiemels | Zendy; Mary V. Relling | Zendy; Jun J. Yang | Zendy; Philip J. Lupo | Zendy; Karen R. Rabin | Zendy

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Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome

Author(s) -

Austin L. Brown,

Adam J. de Smith,

Vincent U. Gant,

Wenjian Yang,

Michael E. Scheurer,

Kyle M. Walsh,

Jonathan M. Chernus,

Noah A. Kallsen,

Stephen Peyton,

Gareth E. Davies,

Erik A. Ehli,

Naomi J. Winick,

Nyla A. Heerema,

Andrew J. Carroll,

Michael J. Borowitz,

Brent L. Wood,

William L. Carroll,

Elizabeth A. Raetz,

Eleanor Feingold,

Meenakshi Devidas,

Lisa F. Barcellos,

Helen M. Hansen,

Libby M. Morimoto,

Alice Y. Kang,

I. Smirnov,

Jasmine Healy,

Caroline Laverdière,

Daniel Sinnett,

Jeffrey W. Taub,

Jillian M. Birch,

Pamela Thompson,

Logan G. Spector,

Maria S. PombodeOliveira,

Andrew T. DeWan,

Charles G. Mullighan,

Stephen P. Hunger,

ChingHon Pui,

Mig L. Loh,

Michael E. Zwick,

Catherine Metayer,

Xiaomei Ma,

Beth A. Mueller,

Stephanie L. Sherman,

Joseph L. Wiemels,

Mary V. Relling,

Jun J. Yang,

Philip J. Lupo,

Karen R. Rabin

Publication year - 2019

Publication title -

blood

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.515

H-Index - 465

eISSN - 1528-0020

pISSN - 0006-4971

DOI - 10.1182/blood.2018890764

Subject(s) - allele , penetrance , biology , cdkn2a , genetics , genome wide association study , locus (genetics) , immunology , single nucleotide polymorphism , gene , genotype , phenotype

The authors report the interaction between Down syndrome, a major genetic leukemia predisposition condition, and inherited genetic alleles associated with increased susceptibility to childhood acute lymphoblastic leukemia.

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