Open AccessLow-Dose Triptolide Enhances Bromodomain Inhibitor JQ1-Induced Apoptosis of Acute Myeloid Leukemia Cells Via Down-Regulation of c-Myc Following RAS/MEK/ERK Inhibition
Author(s) -
Bing Xu,
Yuanfei Shi,
Haijun Zhao,
Yi Qiu
Publication year - 2019
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood-2019-123740
Subject(s) - triptolide , tripterygium wilfordii , myeloid leukemia , mapk/erk pathway , apoptosis , cancer research , bromodomain , leukemia , myeloid , cell growth , pharmacology , medicine , chemistry , kinase , biology , immunology , epigenetics , microbiology and biotechnology , biochemistry , gene , alternative medicine , pathology
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