Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL | Zendy

Frank Vari | Zendy; David Arpon | Zendy; Colm Keane | Zendy; Mark Hertzberg | Zendy; Dipti Talaulikar | Zendy; Sanjiv Jain | Zendy; Qingyan Cui | Zendy; Erica Han | Zendy; Joshua W.D. Tobin | Zendy; Robert Bird | Zendy; Donna Cross | Zendy; Annette Hernandez | Zendy; Clare Gould | Zendy; Simone Birch | Zendy; Maher K. Gandhi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

Author(s) -

Frank Vari,

David Arpon,

Colm Keane,

Mark Hertzberg,

Dipti Talaulikar,

Sanjiv Jain,

Qingyan Cui,

Erica Han,

Joshua W.D. Tobin,

Robert Bird,

Donna Cross,

Annette Hernandez,

Clare Gould,

Simone Birch,

Maher K. Gandhi

Publication year - 2018

Publication title -

blood

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.515

H-Index - 465

eISSN - 1528-0020

pISSN - 0006-4971

DOI - 10.1182/blood-2017-07-796342

Subject(s) - immune system , monocyte , evasion (ethics) , lymphoma , pd l1 , macrophage , immunology , cancer research , biology , immunotherapy , in vitro , biochemistry

Key Points Expansion of PD-1+ CD3−CD56hiCD16-ve NK cells and PD-L1+ monocytes/macrophages is more prominent in cHL than DLBCL. PD-1 blockade reverses the immune evasion mediated by the interaction of PD-1+ NK cells and PD-L1+ monocytes/macrophages.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research