Open AccessSleep and the Gut Microbiome in Psoriasis: Clinical Implications for Disease Progression and the Development of Cardiometabolic Comorbidities
Author(s) -
Bridget Myers,
Vidhatha Reddy,
Nicholas Brownstone,
Si-Wa Chan,
Quinn Thibodeaux,
Hsin-Wen Chang,
Tina Bhutani,
Wilson Liao
Publication year - 2020
Publication title -
journal of psoriasis and psoriatic arthritis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.473
H-Index - 3
eISSN - 2475-5311
pISSN - 2475-5303
DOI - 10.1177/2475530320964781
Subject(s) - psoriasis , medicine , firmicutes , microbiome , gut flora , disease , sleep (system call) , systemic inflammation , immunology , bioinformatics , inflammation , biology , genetics , 16s ribosomal rna , bacteria , computer science , operating system
Sleep dysfunction and sleep disorders are important comorbidities of psoriasis. Not only do these sleep comorbidities contribute to reduced quality of life, but they may also lead to worsening psoriasis and increased susceptibility to cardiometabolic diseases. While psoriasis and sleep dysfunction are thought to be linked by itch, depression, and immune system dysregulation, the relationship between psoriasis and sleep dysfunction is not yet fully understood.