Open AccessVariation in Child Serum Cholesterol and Prevalence of Familiar Hypercholesterolemia: The Health Oriented Pedagogical Project (HOPP)
Author(s) -
Ester Fabiani,
Martin Frank Strand,
Morten Lindberg,
Nandu Goswami,
Per Morten Fredriksen
Publication year - 2022
Publication title -
global pediatric health
Language(s) - English
Resource type - Journals
ISSN - 2333-794X
DOI - 10.1177/2333794x221079558
Subject(s) - medicine , hyperlipidemia , anthropometry , familial hypercholesterolemia , total cholesterol , pediatrics , serum cholesterol , cholesterol , child health , demography , endocrinology , diabetes mellitus , sociology
Early stages of atherosclerosis may develop in childhood due to hyperlipidemia. The aims are to investigate the prevalence of familiar hypercholesterolemia in 6 to 12-year-old children and to study the deviation in cholesterol measures. Anthropometric data and venous blood were collected from children participating in the Health Oriented Pedagogical Project (HOPP). Out of 18 children with TC > 6.0 mmol/L, 15 were tested genetically and none diagnosed with FH. The prevalence of TC > 6.0 mmol/L declined from 1.3% in 2015 to 0.5% in 2016. The mean TC was 4.30 mmol/L both years, which is lower than in earlier studies. Usage of a single TC measurement and a threshold of TC > 6.0 mmol/L in screening children for FH, may not be a good screening strategy. While lipid values have a good reliability across 2 measurements, there are variations in individual TC levels across 1 year.