Open AccessFactors Associated for Mortality of Older People With COVID 19: A Systematic Review and Meta-analysis
Author(s) -
H. D. W. T. Damayanthi,
K.I.P. Prabani,
Ishanka Weerasekara
Publication year - 2021
Publication title -
gerontology and geriatric medicine
Language(s) - English
Resource type - Journals
ISSN - 2333-7214
DOI - 10.1177/23337214211057392
Subject(s) - meta analysis , medicine , dementia , gerontology , older people , systematic review , covid-19 , demography , medline , disease , sociology , political science , infectious disease (medical specialty) , law
Background Whilst people of all ages are affected in some way by COVID-19 virus, older people are at a high mortality risk. This study aimed to systematically review the numerous factors associated with mortality among COVID-19 infected older people.Method PubMed and Science Direct were searched from inception to the April 15, 2021. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement and Joanna Briggs Institute critical appraisal tool to assess the methodological quality of the included studies.Results Of the 4957 studies identified, 20 were included in the qualitative analysis, while 10 were included in the quantitative analysis. Male sex (OR = 2.22, 95% CI = 1.23–3.99), age (over 75 years old) (OR = 3.36, 95% CI = 2.30–4.90), Dementia (OR = 3.69, 95% CI = 1.99–6.83) and Dyspnoea (OR = 3.16, 95% CI = 2.61–3.82), were found to be significantly associated with mortality. There is no significant association between Diabetes, or Hypertension.Conclusion Older age, male gender, dyspnoea and dementia were associated with a greater risk of death of older people from COVID-19 infection. These findings may help health care professionals to identify high-risk groups, facilitate appropriate remedial measures, and control mortality among older people.